Thermo Fisher Scientific COL15A1 Polyclonal Antibody
Human COL15A1 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 및 ICC/IF 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
- Publications: References
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
- Publications: References
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human COL15A1. Recombinant protein control fragment (Product #RP-92318). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2640011 |
Product Specific Information
Immunogen sequence:
RSSQALAFES SAGIFMGNAG ATGLERFTGS LQQLTVHPDP RTPEELCDPE ESSASGETSG LQEADGVAEI LEAVTYTQAS PKEAKVEPIN TPPTPSSPFE DMELSGEPVP E
Highest antigen sequence identity to the following orthologs:
- Mouse: 76%
- Rat: 77%
Target Information
This gene encodes the alpha chain of type XV collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Type XV collagen has a wide tissue distribution but the strongest expression is localized to basement membrane zones, suggesting a role in adhering basement membranes to underlying connective tissue stroma. The proteolytically produced C-terminal fragment of type XV collagen is restin, a potentially antiangiogenic protein closely related to endostatin. Mouse studies indicate that collagen XV deficiency is associated with muscle and microvessel deterioration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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