Thermo Fisher Scientific CD44var (v6) Monoclonal Antibody (9A4), eBioscience
CD44var (v6) 항원을 특이적으로 인식하는 단클론 항체로, 마우스 시료에 적합합니다. ELISA, IHC, Western Blot 등 다양한 어플리케이션에 사용 가능하며, 고순도(>93%)로 제조되었습니다. 세포 표면 CD44 변이체 연구에 유용합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | Assay-Dependent | - |
| Immunohistochemistry (IHC) | Assay-Dependent | 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | - | 1 publication |
| Immunocytochemistry (ICC/IF) | - | 3 publications |
| Flow Cytometry (Flow) | - | 1 publication |
| ELISA | Assay-Dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Mouse |
| Host / Isotype | Rat / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 9A4 |
| Immunogen | Recombinant Mouse CD44var (v6) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10597738 |
| Purity | >93% |
Product Specific Information
Specifically recognizes an epitope encoded by exon v6 on the variant portion of murine CD44.
Standard CD44 (CD44s) lacks the entire variable region and is found mainly in cells of lymphohematopoietic origin.
The multiple isoforms (CD44v; v = variant) contain alternatively spliced exons inserted within the extracellular domain.
These isoforms include CD44v1 through CD44v11.
BMS145 is suitable for ELISA and Western Blot analysis.
Applications Tested: ELISA, Immunohistochemistry, Western Blotting.
Target Information
CD44 is a 100 kDa cell surface glycoprotein widely expressed on human leukocytes, white matter of the brain, and various epithelial cells.
Several isoforms exist, with CD44H being predominant in many normal tissues.
CD44 acts as a receptor for hyaluronic acid (HA) and is involved in cell-cell interactions, adhesion, and migration.
It also participates in lymphocyte activation, recirculation, and homing.
CD44 expression may increase in certain carcinomas, potentially relating to metastatic potential.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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