Thermo Fisher Scientific C11orf30 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Human C11orf30. Recombinant protein control fragment (Product #RP-106311). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:EMSY,uniProtId:Q7Z589-1,ncbiNodeId:9606,antigenRange:908-1055,antigenLength:1322,antigenImageFileName:PA5-65640_EMSY_Q7Z589-1_Rabbit.svg,antigenImageFileNamePDP:PA5-65640_EMSY_Q7Z589-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2663855

Product Specific Information

Immunogen sequence: HTAFTKHSEEL GTEEGEVEEM DTLDPQTGLF YRSALTQSQS AKQQKLSQPP LEQTQLQVKT LQCFQTKQKQ TIHLQADQLQ HKLPQMPQLS IRHQKLTPLQ QEQAQPKPDV QHTQHPMVAK DRQLPTLMAQ PPQTVVQVLA VKTTQQL

Highest antigen sequence identity to the following orthologs - mouse 95%, rat 95%.

Target Information

EMSY is a regulator which is able to repress transcription, possibly via its interaction with a multiprotein chromatin remodeling complex that modifies the chromatin. Its interaction with BRCA2 suggests that it may play a central role in the DNA repair function of BRCA2. As part of a histone H3-specific methyltransferase complex may mediate ligand-dependent transcriptional activation by nuclear hormone receptors. Diseases associated with EMSY include Sporadic Breast Cancer and Breast Cancer.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.