Thermo Fisher Scientific C11orf30 Polyclonal Antibody
Rabbit polyclonal antibody against human C11orf30 (EMSY) for ICC/IF applications. Recognizes recombinant human EMSY protein. High antigen sequence identity with mouse and rat. Suitable for research use only; not for diagnostic or resale.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human C11orf30. Recombinant protein control fragment (Product #RP-106311) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2663855 |
Product Specific Information
Immunogen sequence:
HTAFTKHSEEL GTEEGEVEEM DTLDPQTGLF YRSALTQSQS AKQQKLSQPP LEQTQLQVKT LQCFQTKQKQ TIHLQADQLQ HKLPQMPQLS IRHQKLTPLQ QEQAQPKPDV QHTQHPMVAK DRQLPTLMAQ PPQTVVQVLA VKTTQQL
Highest antigen sequence identity to the following orthologs:
- Mouse: 95%
- Rat: 95%
Target Information
EMSY is a regulator capable of repressing transcription, possibly through interaction with a chromatin remodeling complex that modifies chromatin structure. Its interaction with BRCA2 suggests a role in DNA repair functions of BRCA2. As part of a histone H3-specific methyltransferase complex, EMSY may mediate ligand-dependent transcriptional activation by nuclear hormone receptors.
Diseases associated with EMSY include:
- Sporadic Breast Cancer
- Breast Cancer
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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