Thermo Fisher Scientific MTHFD2 Polyclonal Antibody, MaxPab

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

MTHFD2 (NP_001035499.1, 1 a.a. approximately 248 a.a) full-length human protein.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MKPASISEEE LLNLINKLNN DDNVDGLLVQ LPLPEHIDER RICNAVSPDK DVDGFHVINV GRMCLDQYSM LPATPWGVWE IIKRTGIPTL GKNVVVAGRS KNVGMPIAML LHTDGAHERP GGDATVTISH RYTPKEQLKK HTILADIVIS AAGIPNLITA DMIKEGAAVI DVGINRVHDP VTAKPKLVGD VDFEGVRQKA GYITPVPGGV GPMTVAMLMK NTIIAAKKVL RLEEREVLKS KELGVATN

Target Information

This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in two different transcripts, one protein-coding and the other not protein-coding. This gene has a pseudogene on chromosome 7.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.