Thermo Fisher Scientific GPR17 Monoclonal Antibody (OTI6E2), TrueMAB
GPR17 단백질을 인식하는 Rat IgG1 단클론 항체로, 인간 시료에 반응합니다. IHC(P)에서 사용 가능하며, 신경계의 올리고덴드로사이트 분화 연구에 적합합니다. 비결합형 액상 형태로 -20°C 보관합니다.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): Tested dilution 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rat / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6E2 |
| Immunogen | Synthetic peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
The G-protein-coupled receptor (GPCR) superfamily includes approximately 600–1,000 members and represents the largest known class of molecular targets with therapeutic relevance.
GPR17 is an orphan G protein-coupled receptor implicated in oligodendrocyte differentiation and myelination in the central nervous system.
It is expressed in brain, kidney, heart, and umbilical vein endothelial cells.
GPR17 exhibits dual specificity for uracil nucleotides and cysteinyl leukotrienes and signals through G(i), inhibiting adenylyl cyclase.
It may mediate brain damage by nucleotides and cysteinyl leukotrienes following ischemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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