Thermo Fisher Scientific RAB7 Polyclonal Antibody
RAB7 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot, IHC, ICC 등 다양한 응용에 사용 가능. Human, Mouse, Rat 시료에 반응하며 항원 친화 크로마토그래피로 정제됨. 4°C 또는 -20°C에서 안정하게 보관 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | View 2 publications |
| Immunohistochemistry (IHC) | – | View 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | – |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | View 1 publication |
Product Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human RAB7. Recombinant protein control fragment (Product #RP-89503) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2646252 |
Product Specific Information
Immunogen sequence:
CVLVFDVTAP NTFKTLDSWR DEFLIQASPR DPENFPFVVL GNKIDLENRQ VATKRAQAWC YSKNNIPYFE TSAKEAINVE QAFQTIARNA LKQETEVELY NEFPEPIKLD KNDRAK
Highest antigen sequence identity to the following orthologs:
- Mouse: 100%
- Rat: 99%
Target Information
RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic and endocytic pathways.
This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and from late endosomes to lysosomes. It is also involved in cellular vacuolation induced by the VacA cytotoxin of Helicobacter pylori.
Mutations at conserved residues in this gene have been associated with some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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