Thermo Fisher Scientific BRD2 Polyclonal Antibody
BRD2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunocytochemistry에 사용 가능. 고순도 Affinity chromatography 정제. PBS/glycerol buffer에 보관하며 -20°C에서 안정적 저장.
- 카탈로그번호
- PA5100406
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human BRD2 (Accession P25440), corresponding to amino acid residues Y40–L90 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2849918 |
Product Specific Information
Antibody detects endogenous levels of total BRD2.
Target Information
This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. It associates with transcription complexes and acetylated chromatin during mitosis, selectively binding to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the MHC class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in immune response. It has been implicated in juvenile myoclonic epilepsy, and multiple alternatively spliced variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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