Thermo Fisher Scientific MC1R Monoclonal Antibody (578CT6.2.3)
MC1R 단백질을 인식하는 Mouse IgM 단일클론 항체로, Western blot에 적합합니다. KLH 접합 합성 펩타이드(205–232 aa)로 면역된 항체이며, 1 mg/mL 농도의 액상 형태로 제공됩니다. PBS 버퍼 및 sodium azide를 포함하며, 연구용으로만 사용됩니다.
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Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgM |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 578CT6.2.3 |
| Immunogen | KLH conjugated synthetic peptide between 205–232 amino acids from the central region of human MC1R |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Euglobulin precipitation |
| Storage buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897519 |
Target Information
MC1R, a Melanocortin Receptor, mediates the effects of melanocyte-stimulating hormone (MSH) and adrenocorticotropic hormone (ACTH). MSH and its receptor, MC1R, are key regulators of melanogenesis. They control the relative proportions of red pheomelanin and black photoprotective eumelanin in the skin by increasing the production of eumelanin. Non-functional, truncated forms of the receptor lead to lighter coat color in animals. In contrast, constitutively active receptors lead to darker color.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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