
Thermo Fisher Scientific TRIM22 Monoclonal Antibody (OTI1D11), TrueMAB
인간 TRIM22 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western Blot, IHC, ICC/IF 등에 적합합니다. 고순도 친화 크로마토그래피 정제, 1 mg/mL 농도, PBS/BSA/glycerol 완충액에 보관되며 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1D11 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 61–406 of human TRIM22 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20 °C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
TRIM22 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains—a RING, a B-box type 1, and a B-box type 2—and a coiled-coil region.
It localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that its function may be to mediate interferon’s antiviral effects.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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