Thermo Scientific™

NHS (N-hydroxysuccinimide)

Thermo Scientific Pierce NHS is a chemical modification reagent for converting carboxyl groups to amine-reactive NHS esters for bioconjugation, crosslinking,자세히 알아보기

Thermo Scientific Pierce NHS is a chemical modification reagent for converting carboxyl groups to amine-reactive NHS esters for bioconjugation, crosslinking, labeling and immobilization methods.

Features of NHS:

• Efficiency of EDC-mediated coupling is increased in the presence of NHS
• Amine-reactive NHS esters can be made with any carboxyl-containing molecule
• NHS derivatives of typical small molecules (e.g., biotin) are uncharged, organic-soluble (dissolve first in DMSO) and cell membrane-permeable
• High-purity, crystalline NHS can be used to create high-quality activated derivatives

NHS (N-hydroxysuccinimide), the uncharged analog of Sulfo-NHS (N-hydroxysulfosuccinimide), enables control and modification of carbodiimide crosslinking reactions involving activation of carboxylates (—COOH) for conjugation with primary amines (—NH2).

Product References:
Crosslinker Application Guide -- search for recent literature references for this product

Related Products
Sulfo-NHS (N-hydroxysulfosuccinimide)
EDC (1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride)

사양

화학물질 반응성Amine-Carboxyl

CleavableNo

설명NHS

분자량115.09

페길레이티드No

세포 투과성Not determined

배송 조건Ambient

제품라인Pierce™

라벨링 방법Chemical Labeling

교차결합제 유형Heterobifunctional

반응성 부분Carbodiimide

스페이서Short (<10 Å)

형태Powder

수량25 g

용해도Water

형식Standard

수용성Yes

제품 유형Crosslinker

Unit SizeEach