Thermo Fisher Scientific KCNN2 Polyclonal Antibody
KCNN2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, Western Blot, IHC, ICC/IF 등에 사용 가능. 인간 및 영장류 반응성. Affinity Chromatography로 정제된 Liquid 형태이며, PBS + 2% sucrose buffer에 보관. 연구용 전용 제품.
- 카탈로그번호
- PA541071
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.2–1 µg/mL | View 2 publications |
| Immunohistochemistry (IHC) | 1:300 | - |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | - | View 2 publications |
| Immunocytochemistry (ICC/IF) | 1:300 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human KCNN2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2605451 |
Product Specific Information
Peptide sequence:
KNAAANVLRE TWLIYKNTKL VKKIDHAKVR KHQRKFLQAI HQLRSVKMEQ
Sequence homology:
Cow: 100%
Dog: 100%
Guinea Pig: 100%
Horse: 100%
Human: 100%
Mouse: 100%
Rabbit: 100%
Rat: 100%
Zebrafish: 93%
Target Information
Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and significantly influence neuronal firing patterns. Each component of the AHP is kinetically distinct and mediated by different calcium-activated potassium channels.
The protein encoded by this gene is activated before membrane hyperpolarization and regulates neuronal excitability by contributing to the slow component of synaptic AHP.
It is an integral membrane protein forming a voltage-independent, calcium-activated channel with three other calmodulin-binding subunits.
This gene belongs to the KCNN family of potassium channel genes. Two transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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