Thermo Fisher Scientific FYCO1 Polyclonal Antibody, MaxPab

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG

Class

Polyclonal

Type

Antibody

Immunogen

FYCO1 (AAH07218.1, 1 a.a. approximately 255 a.a) full-length human protein. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:FYCO1,uniProtId:Q9BQS8-1,ncbiNodeId:9606,antigenRange:1-1478,antigenLength:1478,antigenImageFileName:H00079443-B01P_FYCO1_Q9BQS8-1_House_mouse.svg,antigenImageFileNamePDP:H00079443-B01P_FYCO1_Q9BQS8-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MNTKVTSDWY YARSPFLQPK LSSDIVGQLY ELTEVQFDLA SRGFDLDAAW PTFARRTLTT GSSAYLWKPP SRSSSMSSLV SSYLQTQEMV SNFDLNSPLN NEALEGFDEM RLELDQLEVR EKQLQERMQQ LDRENQELRA AVSQQGEQLQ TERERGRTAA EDNVRLTCLV AELQKQWEVT QATQNTVKEL QTCLQALELG AAEKEEDYHT ALRRLESMLQ PLAQELEATR DSLDKKNQHL ASFPGWLAMA LHVGD

Target Information

This gene encodes a protein that contains a RUN domain, FYVE-type zinc finger domain and Golgi dynamics (GOLD) domain. The encoded protein plays a role in microtubule plus end-directed transport of autophagic vesicles through interactions with the small GTPase Rab7, phosphatidylinositol-3-phosphate (PI3P) and the autophagosome marker LC3. Mutations in this gene are a cause of autosomal recessive congenital cataract-2 (CATC2).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.