Thermo Fisher Scientific LOX Monoclonal Antibody (OTI4E3), TrueMAB
LOX 단백질을 인식하는 Mouse monoclonal antibody (OTI4E3). Western blot, IHC, ICC/IF에 사용 가능. Human 시료에 반응하며, Affinity chromatography로 정제된 액상 형태. 세포외기질 형성과 종양 전이 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4E3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 22–168 of human LOX produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.42 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Lysyl oxidase (LOX) is a copper-containing amine oxidase that oxidizes primary amine substrates to reactive aldehydes. It plays a vital role in the formation and repair of the extracellular matrix. LOX is multifunctional, involved in developmental regulation, tumor suppression, cell motility, and cellular senescence. The secreted form of LOX contributes to the invasive properties of hypoxic human cancer cells, making it an important therapeutic target for preventing and treating metastases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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