Thermo Fisher Scientific PPM1A Polyclonal Antibody
Thermo Fisher Scientific의 PPM1A 폴리클로날 항체는 인간, 마우스, 랫트 반응성을 가지며 WB, ICC/IF, ELISA에 적합합니다. 세포 스트레스 반응 및 종양 억제 관련 연구에 유용하며, 고순도 친화 크로마토그래피 정제 제품입니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:50–1:200
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 161–370 of human PPM1A (NP_0050291) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.32 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806645 |
Product Specific Information
- Positive Samples: MCF-7, HeLa, HepG2, SH-SY5Y, Mouse liver, Mouse skeletal muscle, Rat brain
- Cellular Location: Cytoplasm, Lipid-anchor, Membrane, Nucleus, Cytosol
Immunogen sequence:
ILENVEVKGE KPAKLCVIAE CGELKEGDDG GIFPKDGSGD SHPDFPEDAD IDLKDVDKIL LITEDLKNIG NTFFKSQNWE MAIKKYAEVL RYVDSSKAVI ETADRAKLQP IALSCVLNIG ACKLKMSNWQ GAIDSCLEAL ELDPSNTKAL YRRAQGWQGL KEYDQALADL KKAQGIAPED KAIQAELLKV KQKIKAQKDK EKAVYAKMFA
Target Information
PPM1A (Protein phosphatase 1A) is also named PPPM1A and belongs to the PP2C family.
It is a serine/threonine protein phosphatase essential for regulating cellular stress responses in eukaryotes.
PPM1A plays an important role in tumor suppression and negatively controls many signaling pathways critical for trophoblast invasion.
This protein is distributed in both the cytoplasm and nucleus of mammalian cells.
It has two isoforms produced by alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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