Thermo Fisher Scientific NME4 Monoclonal Antibody (OTI5E4)
NME4 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체. Western blot, IHC, ICC, Flow Cytometry에 적합하며, Human 시료 반응성. 고순도 Affinity Chromatography 정제, 안정한 PBS/BSA/glycerol buffer로 보관. 연구용 한정 제품.
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- MA525089
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5E4 |
| Immunogen | Full length human recombinant protein of NME4 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2724845 |
Target Information
NME4 is a protein kinase that transfers a phosphate group from a phosphate donor, typically the γ-phosphate of ATP, onto an acceptor amino acid in a substrate protein. Through this mechanism, protein kinases mediate most signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement, cell movement, apoptosis, and differentiation.
The protein kinase family, comprising over 500 gene products, is one of the largest families in eukaryotes. It is classified into 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
The AGC kinase group includes 63 kinases such as the cyclic nucleotide-regulated protein kinase (PKA/PKG) family, the diacylglycerol-activated/phospholipid-dependent protein kinase C (PKC) family, the RAC/Akt protein kinase family, the G protein-coupled receptor kinases (ARK), and the ribosomal protein S6 kinases (RSK).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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