Thermo Fisher Scientific Human ATG14 Synthetic Peptide
인간 ATG14 단백질의 중심부 18개 아미노산 서열로 구성된 합성 펩타이드. PA5-34453 항체의 블로킹 펩타이드로 사용 가능. 액상 형태, PBS(pH 7.2)와 0.1% BSA 포함. -20°C에서 보관. 연구용으로만 사용.
- 카탈로그번호
- PEP1495
- 판매단위
- pk
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
Product Specific Information
This peptide corresponds to 18 amino acids near the center of human ATG14.
PEP-1495 can be used as a blocking peptide with polyclonal antibody PA5-34453.
Target Information
ATG14 (Autophagy related protein homolog 14) is encoded by the ATG14 gene and is located on chromosome 14 in humans. It is also known as ATG14L or BARKOR (Beclin 1-associated autophagy-related key regulator).
Autophagy is an evolutionarily conserved process that involves recycling of misfolded cellular proteins and degradation of dysfunctional organelles. Autophagy is induced as a cellular response to nutrient stress, which includes the formation of autophagosomes, fusion with lysosomes, and formation of autophagolysosomes.
The Class III PI3-Kinase Vps34 and its interacting partner Beclin 1 form a complex that includes ATG14 (type 1) or UVRAG (type 2). Atg14 guides the type 1 complex to the preautophagosomal structure (PAS) and is critical for the initiation of autophagosome formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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