Thermo Fisher Scientific PACRG Polyclonal Antibody
PACRG 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot, ELISA, IP에 적합합니다. 인간, 생쥐, 닭에서 반응하며, 친화 크로마토그래피로 정제된 액상 항체입니다. 연구용으로만 사용 가능합니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific PACRG Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 – 1:2,000 |
| ELISA (ELISA) | 1:2,000 – 1:10,000 |
| Immunoprecipitation (IP) | 1:500 – 1:3,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Chicken, Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Affinity purified antibody prepared from whole rabbit serum immunized with a synthetic peptide corresponding to an internal region of Human PACRG protein. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.6 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.02M potassium phosphate, pH 7.2, with 0.15M NaCl |
| Contains | 0.01% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use.
This affinity purified antibody is directed against human PACRG protein. A BLAST analysis suggests reactivity with human, mouse, and chicken PACRG proteins based on 100% homology for the immunogen sequence. Cross-reactivity with zebrafish and rat PACRG may occur (94% homology). Expect reactivity with both splice variants of this protein. Cross-reactivity with PACRG homologues from other species has not been determined.
Target Information
PACRG is a conserved protein across metazoans. In vertebrates, this gene is arranged head-to-head with the adjacent parkin gene, associated with autosomal recessive juvenile Parkinson’s disease. Both genes are co-regulated via a bi-directional promoter and are linked to leprosy susceptibility. PACRG forms complexes with chaperones such as HSP70, HSP90, and chaperonin components, and is a component of Lewy bodies in Parkinson’s disease, where it suppresses unfolded Pael receptor-induced neuronal cell death.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.