Thermo Fisher Scientific CD4 Monoclonal Antibody (S3.5), APC-Alexa Fluor 750
인간 CD4 항원을 인식하는 Mouse IgG2a 단일클론 항체로, APC-Alexa Fluor 750 형광체로 결합되어 다중 컬러 유세포분석에 적합합니다. 756/785 nm 파장에서 여기/방출되며, 4°C 암소 보관이 권장됩니다. PBS, sucrose, BSA 버퍼에 0.1% sodium azide 포함.
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Applications
Flow Cytometry (Flow): Assay-dependent
View 2 publicationsMiscellaneous PubMed (Misc): –
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Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Mouse |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | S3.5 |
| Immunogen | Human CD4 |
| Conjugate | APC-Alexa Fluor™ 750 |
| Excitation / Emission Max | 756 / 785 nm |
| Form | Liquid |
| Purification | Purified |
| Storage Buffer | PBS with sucrose, BSA |
| Contains | 0.1% sodium azide |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10375029 |
Additional Formats
- Unconjugated
- Alexa Fluor 405
- Alexa Fluor 488
- Alexa Fluor 700
- APC
- APC-Cyanine5.5
- FITC
- Pacific Blue
- Pacific Orange
- PE
- PE-Alexa Fluor 610
- PE-Alexa Fluor 700
- PE-Cyanine5.5
- PE-Cyanine7
- PE-Texas Red
- PerCP
- Qdot 605
- Qdot 655
- Qdot 705
- Qdot 800
- TRI-COLOR
- Request custom conjugation available
Product Specific Information
The allophycocyanin (APC)-Alexa Fluor™ 750 dye tandem conjugate allows for multicolor measurements using excitation by lasers that emit from 633 to 650 nm.
Target Information
The CD4 antigen is involved in the recognition of MHC class II molecules and serves as a co-receptor for HIV. CD4 is primarily expressed in T helper cells but can also be found in monocytes, macrophages, and dendritic cells. At the tissue level, CD4 expression is detected in thymus, lymph nodes, tonsils, spleen, and certain regions of the brain and gut. CD4 participates in T-cell activation through association with the T-cell receptor complex and the tyrosine kinase Lck, and may play a role in neuronal damage in immune-mediated CNS diseases. Multiple alternatively spliced transcripts have been identified (RefSeq, July 2017).
Analyte Specific Reagent
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