
Thermo Fisher Scientific FAN Polyclonal Antibody
Human FAN 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관됩니다. 연구용으로 TNF 신호전달 관련 연구에 활용 가능합니다.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human FAN. Recombinant protein control fragment (Product #RP-93732) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2641495 |
Product Specific Information
Immunogen sequence:
MVTPLVTNPG HVCITDTNLY FQPLNGYPKP VVQITLQDVR RIYKRRHGLM PLGLEVFCTE DDLCSDIYLK FYEPQDRDDL YFYIATYLEH HVAEHTAESY
Sequence identity with orthologs:
- Mouse: 97%
- Rat: 100%
Target Information
This gene encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor.
It is required for TNF-mediated activation of neutral sphingomyelinase and may play a role in regulating TNF-induced cellular responses such as inflammation.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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