Thermo Fisher Scientific LGR7 Monoclonal Antibody (3E3)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

ELISA (ELISA)

3 ng/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a, kappa

Class

Monoclonal

Type

Antibody

Clone

3E3

Immunogen

LGR7 (NP_067647, 68 a.a. approximately 162 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:LGR7,uniProtId:Q9HBX9-1,ncbiNodeId:9606,antigenRange:68-162,antigenLength:757,antigenImageFileName:H00059350-M01_LGR7_Q9HBX9-1_House_mouse.svg,antigenImageFileNamePDP:H00059350-M01_LGR7_Q9HBX9-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: WSMQFDKYFA SYYKMTSQYP FEAETPECLV GSVPVQCLCQ GLELDCDETN LRAVPSVSSN VTAMSLQWNL IRKLPPDCFK NYHDLQKLYL QNNKI

Target Information

LGR7 is a low density lipoprotein receptor of 757amino acid belonging to the G-protein coupled receptor 1 family with rhodopsin-like receptor activity. It has seven transmembrane region, cysteine-rich motif, 10 LRR domains and 5 N-glycosylation sites in the N terminus. Research reports show that it has receptor for relaxins (RLN1 and RLN2) which stimulates adenylate cyclase activation, substrate adhesion, and chemo migratory capacity of mononuclear leukocytes. LGR7 is critical for mediating these biological responses by use of RNA interference lentiviral short hairpin constructs. It is widely expressed in 86% of 15 primary EC tissue samples including brain, kidney, testis and endometrium.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.