Thermo Fisher Scientific EID3 Monoclonal Antibody (2E5)
EID3 단백질을 인식하는 Thermo Fisher Scientific의 Mouse IgG1 단일클론 항체. Western blot과 ELISA에 적합하며, 인간 시료 반응성. 액상 형태, PBS buffer에 보존, -20°C에서 보관. DNA 복구 관련 연구에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 3 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2E5 |
| Immunogen | EID3 (NP_001008395.1, 1–333 a.a) full-length recombinant protein with GST tag (MW of GST tag = 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MKMDVSVRAA GCSDDLSSGE ADVDPKLLEL TADEEKCRSI RRQYRQLMYC VRQNREDIVS SANNSLTEAL EEANVLFDGV SRTREAALDA RFLVMASDLG KEKAKQLNSD MNFFNQLAFC DFLFLFVGLN WMEGDPDKLS DCDDSIALSF WKAIEKEATS WMVKAETFHF VFGSFKLERS APKPRLEHQK KVRKMEENGN MPTKLQKLDL SSYPEATEKN VERILGLLQT YFRKYPDTPV SYFEFVIDPN SFSRTVENIF YVSFIVRDGF ARIRLDEDRL PILEPMNVNQ MGEGNDSSCH GRKQGVISLT LQEWKNIVAA FEISEAMITY SSY
Target Information
Tissue-specific component of the SMC5-SMC6 complex, which is involved in the repair of DNA double-strand breaks by homologous recombination.
This complex promotes sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks.
It is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components.
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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