Thermo Fisher Scientific SIPA1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human SIPA1. Recombinant protein control fragment (Product #RP-97563). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SIPA1,uniProtId:Q96FS4-1,ncbiNodeId:9606,antigenRange:884-984,antigenLength:1042,antigenImageFileName:PA5-58957_SIPA1_Q96FS4-1_Rabbit.svg,antigenImageFileNamePDP:PA5-58957_SIPA1_Q96FS4-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2647310

Product Specific Information

Immunogen sequence: SPSGSEDKGN PAPELRASFL PRTLSLRNSI SRIMSEAGSG TLEDEWQAIS EIASTCNTIL ESLSREGQPI PESGDPKGTP KSDAEPEPGN LSEKVSHLES M

Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 82%.

Target Information

The product of this gene is a mitogen induced GTPase activating protein. It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.