Thermo Fisher Scientific UNC13B Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:1,000-1:2,500

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human UNC13B. Recombinant protein control fragment (Product #RP-93102). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:UNC13B,uniProtId:O14795-1,ncbiNodeId:9606,antigenRange:272-343,antigenLength:1591,antigenImageFileName:PA5-55091_UNC13B_O14795-1_Rabbit.svg,antigenImageFileNamePDP:PA5-55091_UNC13B_O14795-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.4 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2649265

Product Specific Information

Immunogen sequence: SQLSELDQYH EQDDDHRETD SIHSCHSSHS LSRDGQAGFG EQEKPLEVTG QAEKEAACEP KEMKEDATTH PP

Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 69%.

Target Information

Plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. Is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-depending refilling of readily releasable vesicle pool (RRP). Essential for synaptic vesicle maturation in a subset of excitatory/glutamatergic but not inhibitory/GABA-mediated synapses.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.