Thermo Fisher Scientific Plectin Polyclonal Antibody
Thermo Fisher Scientific의 Plectin Polyclonal Antibody는 인간 Plectin 단백질을 인식하는 토끼 다클론 항체로, WB, IHC, ICC, IP 등 다양한 응용에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 안정적인 PBS 완충액에 보관됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:10,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 | - |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | View 1 publication |
| Immunoprecipitation (IP) | Assay-dependent | - |
Product Specifications
| Category | Specification |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human Plectin. Recombinant protein control fragment (Product # RP-93970) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2645646 |
Product Specific Information
Immunogen sequence:
TEIIRQQGLA SYDYVRRRLT AEDLFEARII SLETYNLLRE GTRSLREALE AESAWCYLYG TGSVAGVYLP GSRQTLSIYQ ALKKGLLSAE VARLLLEAQA A
Antigen sequence identity:
- Mouse: 90%
- Rat: 92%
Target Information
Plectin is a prominent member of the plakin (cytolinker) family, which interlinks different elements of the cytoskeleton. These large, multi-domain proteins maintain cell and tissue integrity, orchestrate dynamic changes in cytoarchitecture, and serve as scaffolding platforms for signaling complex assembly and regulation.
Plectin is expressed as multiple isoforms from a single gene on human chromosome 8, with expression patterns varying by tissue type and developmental stage, contributing to distinct cellular functions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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