Thermo Fisher Scientific CENPT Polyclonal Antibody
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Applications
Tested Dilution
Publications
Western Blot (WB)
-
View 1 publication 1 publication
Immunocytochemistry (ICC/IF)
0.25-2 µg/mL
View 1 publication 1 publication
Product Specifications
Species Reactivity
Human
Published species
Mouse
Host/Isotype
Rabbit / IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human CENPT. Recombinant protein control fragment (Product #RP-104730). if (typeof window.$mangular === undefined
|| !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{
targetFamily:
CENPT,
uniProtId:
Q96BT3-1,
ncbiNodeId:
9606,
antigenRange:
60-166,
antigenLength:
561,
antigenImageFileName:
PA5-83540_CENPT_Q96BT3-1_Rabbit.svg,
antigenImageFileNamePDP:
PA5-83540_CENPT_Q96BT3-1_Rabbit_PDP.jpeg,
sortOrder:
1}\]
; $mangular.isB2BCMGT = false
; $mangular.isEpitopesModalImageMultiSizeEnabled = true
;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
0.20 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2790693
Product Specific Information
Immunogen sequence: RGRSHGARSV GRSAHIQASG HLEEQTPRTL LKNILLTAPE SSILMPESVV KPVPAPQAVQ PSRQESSCGS LELQLPELEP PTTLAPGLLA PGRRKQRLRL SVFQQGV
Target Information
Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. Part of a nucleosome-associated complex that binds specifically to histone H3-containing nucleosomes at the centromere, as opposed to nucleosomes containing CENPA. Component of the heterotetrameric CENP-T-W-S-X complex that binds and supercoils DNA, and plays an important role in kinetochore assembly. CENPT has a fundamental role in kinetochore assembly and function. It is one of the inner kinetochore proteins, with most further proteins binding downstream. Required for normal chromosome organization and normal progress through mitosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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