Thermo Fisher Scientific ARID5B Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human MRF2. Recombinant protein control fragment (Product #RP-90906). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ARID5B,uniProtId:Q14865-1,ncbiNodeId:9606,antigenRange:853-990,antigenLength:1188,antigenImageFileName:PA5-53270_ARID5B_Q14865-1_Rabbit.svg,antigenImageFileNamePDP:PA5-53270_ARID5B_Q14865-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2644101

Product Specific Information

Immunogen sequence: TSKYPSRDMY RESENSSFPS HRHQEKLHVN YLTSLHLQDK KSAAAEAPTD DQPTDLSLPK NPHKPTGKVL GLAHSTTGPQ ESKGISQFQV LGSQSRDCHP KACRVSPMTM SGPKKYPESL SRSGKPHHVR LENFRKME

Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 24%.

Target Information

ARID5B encodes a member of the AT-rich interaction domain (ARID) family of DNA binding proteins. The encoded protein forms a histone H3K9Me2 demethylase complex with PHD finger protein 2 and regulates the transcription of target genes involved in adipogenesis and liver development. ARID5B also plays a role in cell growth and differentiation of B-lymphocyte progenitors, and single nucleotide polymorphisms in this gene are associated with acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.