Thermo Fisher Scientific ARID5B Polyclonal Antibody
ARID5B 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, 인간 시료에 반응합니다. ICC/IF에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS 기반 용액 형태로 제공되며, 장기 보관 시 -20°C에서 냉동 보관 권장됩니다.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MRF2 (Product #RP-90906) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2644101 |
Product Specific Information
Immunogen sequence:
TSKYPSRDMY RESENSSFPS HRHQEKLHVN YLTSLHLQDK KSAAAEAPTD DQPTDLSLPK NPHKPTGKVL GLAHSTTGPQ ESKGISQFQV LGSQSRDCHP KACRVSPMTM SGPKKYPESL SRSGKPHHVR LENFRKME
- Highest antigen sequence identity to the following orthologs:
- Mouse: 82%
- Rat: 24%
Target Information
ARID5B encodes a member of the AT-rich interaction domain (ARID) family of DNA binding proteins.
The encoded protein forms a histone H3K9Me2 demethylase complex with PHD finger protein 2 and regulates transcription of genes involved in adipogenesis and liver development.
ARID5B also plays a role in cell growth and differentiation of B-lymphocyte progenitors, and SNPs in this gene are associated with acute lymphoblastic leukemia.
Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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