Thermo Fisher Scientific Human HIPK3 (YAK1), His Tag Recombinant Protein
인간 HIPK3 (YAK1) 재조합 단백질로 세린/트레오닌 키나아제 활성을 연구에 활용 가능. His-tag 부착 및 곤충 세포 발현 시스템 사용. 고순도 정제된 액상 형태로 제공되며, -80°C에서 안정적으로 보관 가능. 세포 신호전달 및 암 관련 연구에 적합.
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Thermo Fisher Scientific Human HIPK3 (YAK1), His Tag Recombinant Protein
Applications
- Kinase Assay (KA)
Tested Dilution
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Expression System | Insect cells |
| Amino acid sequence | 163–562 |
| Tag | His-tag |
| Molecular weight | 49.7 kDa |
| Class | Recombinant |
| Type | Protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Purified |
| Storage buffer | 50 mM Tris HCl (pH 7.5), 150 mM NaCl, 0.02% Triton X-100, 50% glycerol, 2 mM DTT, 0.5 mM EDTA |
| Contains | No preservative |
| Storage conditions | -80°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Dry ice |
Product Specific Information
- For maximum recovery, please spin prior to use.
- Aliquots of 5 µg, 10 µg, and 20 µg sizes are not recommended; use materials in original packaging until exhausted.
- For larger sizes, reduce freeze/thaw cycles by preparing aliquots (do not prepare aliquots below 20 µL).
- Never store kinase diluted.
- Properly stored at -80°C, guaranteed for 6 months from date of purchase.
- Protein Form: Catalytic
Target Information
HIPK3 is a serine/threonine kinase involved in signal transduction, cellular communication, and multidrug resistance of tumors. It phosphorylates FADD and negatively regulates apoptosis by promoting FADD phosphorylation.
This kinase enhances androgen receptor-mediated transcription and may act as a transcriptional corepressor for NK homeodomain transcription factors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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