Thermo Fisher Scientific PD-L1 Recombinant Rabbit Monoclonal Antibody (BLR227K)
PD-L1 단백질을 인식하는 재조합 토끼 단클론 항체로, WB, Flow Cytometry, IP에 사용 가능. 인간 PD-L1에 반응하며 HEK293F에서 발현. 고순도 정제된 액상 형태로 연구용 면역 분석에 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Flow Cytometry (Flow) | 2 µL/10^6 cells |
| Immunoprecipitation (IP) | 20 µL/mg of lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | BLR227K |
| Immunogen | Recombinant protein representing the extracellular domain of Human Programmed cell death 1 ligand 1 (residues 19–238) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 100 µg/mL |
| Purification | Purified |
| Storage Buffer | BBS, pH 8.2, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Flow Cytometry: Cells fixed in 4% formaldehyde and permeabilized with 90% methanol.
Target Information
Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a B7 family member that interacts with the programmed death receptor 1 (PD-1), negatively regulating T-cell receptor (TCR) signaling. PD-L1 ligation decreases TCR-mediated proliferation and cytokine production. PD-L1 expression is abundant in various murine and human cancers and can be up-regulated by IFN-gamma stimulation, suggesting its role in tumor immune evasion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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