Thermo Fisher Scientific FAM21A Polyclonal Antibody
Human FAM21A 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 등 다양한 응용에 적합. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보존. 연구용으로만 사용 가능.
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Thermo Fisher Scientific FAM21A Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:20–1:50 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein corresponding to Human FAM21A. Recombinant protein control fragment (Product #RP-108450) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2856924 |
Product Specific Information
Immunogen sequence:
GIQAKTTKPK SRSAQAAPEP RFEHKVSNIF DDPLNAFGGQ
Target Information
FAM21A acts as a component of the WASH core complex, which regulates actin polymerization on endosomes by recruiting and activating the Arp2/3 complex. It mediates endosomal membrane association via phospholipid and VPS35 binding, facilitating vesicle scission and trafficking. Also involved in endosome-to-plasma membrane recycling of SNX27-retromer-dependent cargo proteins such as GLUT1. Required for association and recruitment of several retromer and CCC complex subunits.
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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