Thermo Fisher Scientific MAP3K13 Monoclonal Antibody (OTI5A2), TrueMAB

Thermo Fisher Scientific MAP3K13 Monoclonal Antibody (OTI5A2), TrueMAB

Applications

• Western Blot (WB): Tested dilution 1:500

Product Specifications

Target Information

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the γ phosphate of ATP, onto an acceptor amino acid in a substrate protein. Through this mechanism, protein kinases mediate most signal transduction in eukaryotic cells, regulating processes such as metabolism, transcription, cell cycle progression, cytoskeletal rearrangement, cell movement, apoptosis, and differentiation.

With more than 500 gene products, the protein kinase family is one of the largest in eukaryotes. It is classified into eight major groups based on sequence comparison of tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine-like kinase (TLK) group includes MLK (mixed-lineage kinase), LISK (LIMK/TESK), IRAK (interleukin-1 receptor-associated kinase), Raf, RIPK (receptor-interacting protein kinase), and STRK (activin and TGF-beta receptor) families.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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