Thermo Fisher Scientific SMEK1 Polyclonal Antibody
Human SMEK1 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 및 ICC/IF 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 및 40% glycerol buffer에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SMEK1. Recombinant protein control fragment (Product #RP-89035). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2647633 |
Product Specific Information
Immunogen sequence:
DGEAVVSPSD KTKNDDDIMD PISKFMERKK LKESEEKEVL LKTNLSGRQS PSFKLSLSSG TKTNLTSQSS TTNLPGSPGS PGSPGSPGSP GSVPKNTSQT AAITTKGGLV GLVDYPDDDE DDDEDEDK
- Highest antigen sequence identity to the following orthologs:
- Mouse: 98%
- Rat: 97%
Target Information
Regulatory subunit of serine/threonine-protein phosphatase 4.
May regulate the activity of PPP4C at centrosomal microtubule organizing centers.
The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on Ser-140 (gamma-H2AFX), generated during DNA replication and required for DNA double-strand break (DSB) repair.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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