
Thermo Fisher Scientific TWISTNB Polyclonal Antibody
TWISTNB 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, WB, IHC, ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며 인체 반응성, 액상 형태, 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TWISTNB. Recombinant protein control fragment (Product #RP-92636). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2649130 |
Product Specific Information
Immunogen sequence:
QTMEINMGDE LEFEVFRLDS DAAGVFCIRG KLNITSLQFK RSEVSEEVTE NGTEEAAKKP KKKKKKKDPE TYEVDSGTTK LAD
Highest antigen sequence identity to the following orthologs:
- Mouse: 66%
- Rat: 66%
Target Information
DNA-directed RNA polymerase I subunit RPA43 or Twist neighbor protein (Twistnb) belongs to the eukaryotic RPA43 RNA polymerase subunit family.
It catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Twistnb is a component of RNA polymerase I which synthesizes ribosomal RNA precursors.
It is widely expressed in all fetal and adult tissues, with highest expression in fetal lung, liver, and kidney, and low expression in all adult tissues.
Twist genes are essential for embryonic development and are conserved from jellyfish to human.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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