Thermo Fisher Scientific Integrin alpha V/CD51 Polyclonal Antibody
Integrin alpha V/CD51에 특이적인 Rabbit Polyclonal Antibody로, WB, IHC, ICC, Flow, ELISA 등 다양한 응용에 적합. Human, Mouse, Rat 반응성. Protein A 정제, 1 mg/mL 농도, -20°C 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:20–1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human Integrin alpha V, amino acids 51–150 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
ITAGV encodes the integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, which combine with multiple integrin beta chains (β1, β3, β5, β6, β8) to form different integrins.
Among these, the αVβ3 integrin, known as the Vitronectin receptor (VNR), is well-studied and mediates adhesion and signal transduction. Integrin β3 is found with the αIIb chain in platelets and participates in cell adhesion and cell-surface mediated signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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