Thermo Fisher Scientific PPBP Polyclonal Antibody
PPBP 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human, Mouse, Rat 시료에 반응합니다. Western blot, IHC, ICC, ELISA 등 다양한 응용에 적합하며, Affinity chromatography로 정제된 고순도 항체입니다. PBS/50% glycerol 용액 형태로 -20°C 보관합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 | - |
| ELISA | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PPBP (Accession P02775), corresponding to amino acid residues L17–K67. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899706 |
Product Specific Information
Antibody detects endogenous levels of total CXCL7/PBP.
Target Information
Members of the α-chemokine subfamily of inducible, secreted, pro-inflammatory cytokines contain a Cys-X-Cys motif and are chemotactic for neutrophils. The platelet basic protein (PBP), a member of this family, is stored in platelet α-granules and released upon activation. Proteolytic cleavage produces several peptides including mature PBP, connective tissue-activating peptide III (CTAP III or LA-PF4), β-thromboglobulin (β-TG), and neutrophil-activating peptide 2 (NAP-2). These peptides mediate inflammation and wound healing, with NAP-2 promoting neutrophil chemotaxis and degranulation. The human PBP gene is located on chromosome 4q12–q13.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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