Thermo Fisher Scientific PARVA Polyclonal Antibody
PARVA 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. 인간 및 생쥐 반응성이 있으며, 합성 펩타이드 면역원으로 제작되었습니다. 고순도 IgG 분획, 액상 형태로 제공되며 4°C 단기 보관 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide gtlarrkkakevsefqeeg conjugated to KLH, corresponding to amino acids 35–53 of Mouse Parvin alpha. The sequence is identical in human actopaxin and has considerable homology (70%) with beta parvin/affixin, but no homology with gamma parvin. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 8.3 mg/mL |
| Purification | IgG fraction |
| Storage buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_795139 |
Product Specific Information
- Recommended positive controls: ECV304
- PA1-25074 is expected to cross react with human (94% conserved) and rat (100% conserved) due to sequence homology.
- The PA1-25074 immunogen is a synthetic peptide gtlarrkkakevsefqeeg conjugated to KLH, corresponding to amino acids 35–53 of Mouse Parvin alpha.
The sequence is identical in human actopaxin and has considerable homology (70%) with beta parvin/affixin, but no homology with gamma parvin.
Target Information
The protein encoded by this gene is a transcription factor that contains C2H2-type zinc-fingers.
It also contains a positive regulatory domain, which has been found in several other zinc-finger transcription factors including those involved in B cell differentiation and tumor suppression.
Studies of the mouse counterpart suggest that this protein may be involved in the development of the central nervous system (CNS), as well as in the pathogenesis of neuronal storage disease.
Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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