Thermo Fisher Scientific PARVA Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:3,000

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide gtlarrkkakevsefqeeg conjugated to KLH, corresponding to amino acids 35-53 of Mouse Parvin alpha. The sequence is identical in human actopaxin and has considerable homology (70%) with beta parvin/affixin, but no homology with gamma parvin if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PARVA,uniProtId:Q9EPC1-1,ncbiNodeId:10090,antigenRange:35-53,antigenLength:372,antigenImageFileName:PA1-25074_PARVA_Q9EPC1-1_Rabbit.svg,antigenImageFileNamePDP:PA1-25074_PARVA_Q9EPC1-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

8.3 mg/mL

Purification

IgG fraction

Storage buffer

PBS, pH 7.4

Contains

15mM sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_795139

Product Specific Information

Recommended positive controls: ECV304.

PA1-25074 is expected to cross react with human (94% conserved) and rat (100% conserved) due to sequence homology.

The PA1-25074 immunogen is a synthetic peptide gtlarrkkakevsefqeeg conjugated to KLH, corresponding to amino acids 35-53 of Mouse Parvin alpha. The sequence is identical in human actopaxin and has considerable homology (70%) with beta parvin/affixin, but no homology with gamma parvin.

Target Information

The protein encoded by this gene is a transcription factor that contains C2H2-type zinc-fingers. It also contains a positive regulatory domain, which has been found in several other zinc-finger transcription factors including those involved in B cell differentiation and tumor suppression. Studies of the mouse counterpart suggest that this protein may be involved in the development of the central nerve system (CNS), as well as in the pathogenesis of neuronal storage disease. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.