Thermo Fisher Scientific NFS1 Polyclonal Antibody
Thermo Fisher Scientific의 NFS1 Polyclonal Antibody는 인간 NFS1 단백질을 인식하는 토끼 유래 항체로, Western blot에 최적화되어 있습니다. 단백질 A로 정제되었으며, PBS와 2% sucrose buffer에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human NFS1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2576279 |
Product Specific Information
Peptide sequence:
TTQTEHKCVL DSCRSLEAEG FQVTYLPVQK SGIIDLKELE AAIQPDTSLV
Sequence homology:
Cow: 100%
Dog: 93%
Guinea Pig: 100%
Horse: 100%
Human: 100%
Mouse: 100%
Rabbit: 93%
Rat: 100%
Yeast: 92%
Target Information
NFS1 (nitrogen fixation 1), also known as NIFS or IscS (cysteine desulfurase), is a member of the class V pyridoxal-phosphate-dependent aminotransferase family. It localizes to the cytoplasm or mitochondrion depending on cytosolic pH. Highest expression levels of NFS1 are found in heart and skeletal muscle, with lower levels in liver, brain, and pancreas. NFS1 catalyzes the removal of sulfur from cysteine to form alanine, supplying inorganic sulfur for iron-sulfur (Fe-S) clusters. These clusters act as essential cofactors in electron transfer, enzymatic catalysis, and maintenance of DNA repair enzyme structural integrity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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