Thermo Fisher Scientific ZGLP1 Polyclonal Antibody
Thermo Fisher Scientific의 ZGLP1 Polyclonal Antibody는 인간 ZGLP1 단백질을 인식하는 토끼 다클론 항체입니다. IHC(P) 및 ICC/IF에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용되며, 장기 보관 시 -20°C 보관을 권장합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ZGLP1. Recombinant protein control fragment (Product # RP-99247) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2649919 |
Product Specific Information
Immunogen sequence:
LLDRDSKDTQ TRISQKGRRL QPPGTPSAPP QRRPRKQLNP CRGTERVDPG FEGVTLKFQI KPDSSLQIIP TYSLPCSSRS QE
Antigen sequence identity:
- Mouse: 50%
- Rat: 50%
Target Information
Glucagon is initially synthesized as proglucagon, a 180 amino acid precursor that undergoes proteolytic cleavage. It contains regions corresponding to Glucagon itself, a signal peptide, spacer regions, and two Glucagon-like peptide sequences.
GLP1 is encoded by the fourth exon of the six in the human Glucagon gene. It is 37 amino acids in length and shares 48% sequence homology with Glucagon, likely arising from gene duplication. The sequence of GLP1 is conserved across many species, suggesting a specific biological function.
GLP1 is a potent insulin secretagogue that renders pancreatic beta cells glucose-competent and may have potential in diabetes mellitus research and treatment.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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