Thermo Fisher Scientific ERCC1 Monoclonal Antibody (OTI1B3), TrueMAB
ERCC1 단백질을 인식하는 Mouse IgG1 단일클론 항체로 다양한 응용 분야(WB, IHC, ICC, Flow)에 사용 가능. 높은 특이성과 재현성을 제공하며, 액상 형태로 보관 용이. 연구용 DNA 손상 복구 관련 실험에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1B3 |
| Immunogen | Full length human recombinant protein of human ERCC1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.85 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
ERCC1 is a non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5′-incision during DNA repair. It functions with SLX4 in the first step of interstrand cross-link (ICL) repair and participates in processing anaphase bridge-generating DNA structures that can lead to cytokinesis failure. ERCC1 is also required for homology-directed repair (HDR) of DNA double-strand breaks in conjunction with SLX4. (Source: UniProt)
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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