Thermo Fisher Scientific SLC39A5 Monoclonal Antibody (OTI2F2), TrueMAB
SLC39A5 단백질을 인식하는 Mouse IgG1 단클론 항체로 Western Blot 및 IHC(P) 검증 완료. 인간 시료 반응성, 1 mg/mL 농도의 동결건조 형태. 연구용으로만 사용 가능하며, 아연 수송 관련 ZIP5 단백질 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2F2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 48–178 of human SLC39A5 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The zinc transporter ZIP5 (SLC39A5) is a member of the divalent ion transporter family. Zinc is essential for cellular growth, development, and differentiation. ZIP5 is closely related to ZIP4 and is expressed in tissues such as intestine, pancreas, liver, and kidney. Unlike ZIP4, ZIP5 localizes to the basolateral membrane in kidney cells and its activity is not downregulated by zinc repletion.
Recent studies indicate reciprocal regulation between ZIP4 and ZIP5, with ZIP5 mRNA translation decreasing and ZIP5 protein being internalized and degraded under zinc deficiency conditions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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