Thermo Fisher Scientific ASB2 Monoclonal Antibody (OTI4C2)
ASB2 단백질을 인식하는 마우스 단클론 항체로, Western blot 및 IHC(P) 분석에 적합합니다. 인체 유래 단백질(aa 1–300)을 면역원으로 제작되었으며, 액상 형태로 제공됩니다. 고순도 친화 크로마토그래피 정제, -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4C2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–300 of ASB2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2723916 |
Target Information
The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequences and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signaling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. This gene is induced by all-trans retinoic acid. In myeloid leukemia cells, expression of this encoded protein has been shown to induce growth inhibition and chromatin condensation. Multiple alternatively spliced transcript variants have been described for this gene, but their full-length sequences are not known.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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