Thermo Fisher Scientific MGAT5B Polyclonal Antibody
Rabbit polyclonal antibody targeting human MGAT5B for ICC/IF applications. Recognizes glycosyltransferase involved in N- and O-glycan modification. Supplied as liquid, unconjugated form, purified by antigen affinity chromatography. For research use only.
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Applications
- Immunocytochemistry (ICC/IF)
Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human MGAT5B. Recombinant protein control fragment (Product #RP-105719) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2663448 |
Product Specific Information
Immunogen sequence:
RTKRLTAQWAL AAQRLAQKLG ATQRDQKQIL VHIGFLTEES GDVFSPRVLK GGPLGEMVQW ADILTALYVL GHGLRVTVSL KELQSNLGVP PGRGSCPLTM PLPFDLIYTD YHGLQQMKRH MGLSFKKYRC RIRVID
Highest antigen sequence identity to the following orthologs:
- Mouse: 89%
- Rat: 88%
Target Information
Glycosyltransferase that acts on alpha-linked mannose of N-glycans and O-mannosyl glycans. Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to the beta 1-6 linkage of the mannose residue of GlcNAcbeta1,2-Manalpha on both the alpha1,3- and alpha1,6-linked mannose arms in the core structure of N-glycan.
Also acts on the GlcNAcbeta1,2-Manalpha1-Ser/Thr moiety, forming a 2,6-branched structure in brain O-mannosyl glycan. Plays an active role in modulating integrin and laminin-dependent adhesion and migration of neuronal cells via its activity in the O-mannosyl glycan pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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