Thermo Fisher Scientific alpha-1a Adrenergic Receptor Polyclonal Antibody
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카탈로그 번호 | CAS 번호 | 설명 | 상태 | 단위 | 판매가 | 할인가 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
PA5143004 | - | Thermo Fisher Scientific PA5143004 alpha-1a Adrenergic Receptor Polyclonal Antibody 100 ug pk | 재고문의 | pk | 683,000원 | - | 751,300원 |
다른 상품 둘러보기
Applications
Tested Dilution
Publications
Western Blot (WB)
1-3 µg/mL
Product Specifications
Species Reactivity
Human
Host/Isotype
Goat / IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide with sequence C-PSLDKNHQVPTIK. if (typeof window.$mangular === undefined
|| !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{
targetFamily:
alpha-1a Adrenergic Receptor,
uniProtId:
P35348-1,
ncbiNodeId:
9606,
antigenRange:
441-453,
antigenLength:
466,
antigenImageFileName:
PA5-143004_alpha-1a_Adrenergic_Receptor_P35348-1_Goat.svg,
antigenImageFileNamePDP:
PA5-143004_alpha-1a_Adrenergic_Receptor_P35348-1_Goat_PDP.jpeg,
sortOrder:
1}\]
; $mangular.isB2BCMGT = false
; $mangular.isEpitopesModalImageMultiSizeEnabled = true
;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2933644
Product Specific Information
Additional Information: This antibody is expected to recognize isoform 1 (NP_000671.2) only.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:16,000.
Target Information
Adrenergic receptors (ARs) are members of the 7-transmembrane domain G-protein-coupled receptor superfamily that bind the endogenous catecholamines epinephrine and norepinephrine. Pharmacological, structural, and molecular cloning data indicate significant heterogeneity within this receptor family. Nine receptor subtypes have been identified thus far including three alpha-1 AR subtypes (1A/D, 1B, and 1C), three alpha-2 ARs (2A, 2B, and 2C), and three beta AR subtypes (1, 2, and 3). ARs participate in either the onset or maintenance of several disease states including hypertension, cardiac dysfunction (congestive heart failure, ischemia, arrhythmias), diabetes, glaucoma, depression, and impotence. A1AR subtypes are found in numerous tissues and have been shown to be involved in the regulation of blood pressure due to changes in vascular tone and cardiac output. Effects on uterine contraction, hepatic glucose metabolism, heat shock protein 70 (HSP70), proto-oncogene expression, and mitogenesis have been linked to A1AR activation. Norepinephrine can increase nitric oxide synthase (NOS) levels in the hypothalamus by activating alpha-1 AR which may indirectly suppress the release of luteinizing hormone (LH), the androgens, estrogen, and progesterone.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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