Thermo Fisher Scientific Phospho-KSR1 (Ser392) Recombinant Rabbit Monoclonal Antibody (KSR1S392-3A4), PE

Applications

Tested Dilution

Publications

Flow Cytometry (Flow)

5 µL/1x10^6 cells

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG, kappa

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

KSR1S392-3A4

Immunogen

A synthetic phosphor-peptide corresponding to residues surrounding Ser392 of human phospho KSR1. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:KSR1,uniProtId:Q8IVT5-1,ncbiNodeId:9606,antigenRange:392,antigenLength:923,antigenImageFileName:MA5-37292_KSR1_Q8IVT5-1_Rabbit.svg,antigenImageFileNamePDP:MA5-37292_KSR1_Q8IVT5-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

PE PE PE

View additional formats

• Unconjugated
• FITC
• Request custom conjugation

Excitation/Emission Max

565/576 nm View spectra

Form

Liquid

Purification

Protein A/G

Storage buffer

PBS with 0.20% BSA

Contains

0.09% sodium azide

Storage conditions

4° C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2897226

Target Information

Part of a multiprotein signaling complex which promotes phosphorylation of Raf family members and activation of downstream MAP kinases. Independently of its kinase activity, acts as MAP2K1/MEK1 and MAP2K2/MEK2-dependent allosteric activator of BRAF; upon binding to MAP2K1/MEK1 or MAP2K2/MEK2, dimerizes with BRAF and promotes BRAF-mediated phosphorylation of MAP2K1/MEK1 and/or MAP2K2/MEK2 (PubMed:29433126). Promotes activation of MAPK1 and/or MAPK3, both in response to EGF and to cAMP. Its kinase activity is unsure. Some protein kinase activity has been detected in vitro, however the physiological relevance of this activity is unknown. [UniProt]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.