Thermo Fisher Scientific NAPE PLD Polyclonal Antibody
Rabbit polyclonal antibody against human NAPE-PLD. Validated for Western blot. Recognizes N-terminal region (aa 71-120). Suitable for detecting NAPE-PLD involved in endocannabinoid signaling. For research use only.
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Applications
Western Blot (WB)
- Tested Dilution: 0.2–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human NAPE-PLD (aa 71–120) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2607286 |
Product Specific Information
Peptide sequence:
TWKNPSIPNV LRWLIMEKDH SSVPSSKEEL DKELPVLKPY FITNPEEAGV
Sequence homology:
Cow: 100%
Dog: 93%
Guinea Pig: 100%
Horse: 100%
Human: 100%
Mouse: 100%
Rabbit: 100%
Rat: 100%
Target Information
N-Acylphosphatidylethanolamine (NAPE)-hydrolyzing phospholipase D (NAPE-PLD) is a membrane-bound enzyme that releases the endocannabinoid anandamide and other bioactive N-acylethanolamines from their corresponding NAPEs in animal tissues.
It is expressed by specific populations of neurons in the brain and targeted to axonal processes.
NAEs generated by NAPE-PLD in axons may act as anterograde synaptic signaling molecules that regulate postsynaptic neuronal activity.
NAPE-PLD also catalyzes the hydrolysis of NAPE to generate OEA (oleoylethanolamide), a lipid amide that inhibits food intake in rodents.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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