Thermo Fisher Scientific RAB8A Polyclonal Antibody
RAB8A 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 적합하며 인간, 마우스, 비인간 영장류, 랫트에서 반응. 고순도 친화 크로마토그래피 정제, PBS/glycerol buffer, -20°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human RAB8A (Accession P61006), corresponding to amino acid residues I156–L206 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2853412 |
Product Specific Information
Antibody detects endogenous levels of total RAB8A.
Target Information
The protein encoded by this gene is a member of the RAS superfamily, which are small GTP/GDP-binding proteins with an average size of about 200 amino acids.
RAB/YPT family proteins may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane.
This protein shares 97%, 96%, and 51% similarity with dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively, and contains four GTP/GDP-binding sites present in all RAS proteins.
It includes a C-terminal CAAX motif characteristic of many RAS superfamily members but absent in YPT1 and most RAB proteins.
Although isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrated.
This oncogene is located approximately 800 kb distal to MY09B on chromosome 19p13.1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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