Thermo Fisher Scientific Rho Pan Polyclonal Antibody
Rho 관련 GTP 결합 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC에 적합합니다. 동결건조 형태로 제공되며, 재구성 후 안정성을 위해 글리세롤 첨가 가능. 세포 형태, 부착, 이동 연구에 활용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 10–50 µg/mL |
| Immunohistochemistry (IHC) | 10–50 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from human Rho-related GTP-binding proteins (RhOA, RhOB, RhOC, RhOF, RhOQ) and RAC1, RAC2, RAC3, and CDC42 conjugated to an immunogenic carrier protein was used as the antigen. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10981540 |
Product Specific Information
- Glycerol (1:1) may be added for additional stability.
- Reconstitute in 500 µL of sterile water.
- The peptide is homologous in many other species.
Target Information
This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades.
Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility.
The protein encoded by this gene is prenylated at its C-terminus and localizes to the cytoplasm and plasma membrane.
It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis.
Multiple alternatively spliced variants, encoding the same protein, have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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