Thermo Fisher Scientific PGRMC2 Polyclonal Antibody
Thermo Fisher Scientific의 PGRMC2 Polyclonal Antibody는 인간, 마우스, 랫트 시료에서 PGRMC2 단백질을 검출하는 고품질 항체입니다. Western blot, IHC, ICC/IF에 적합하며, 고순도 친화 크로마토그래피로 정제되었습니다. 연구용으로 안정적이며 -20°C에서 보관 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human PGRMC2 (Accession O15173), amino acid residues F190–D223 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851095 |
Product Specific Information
This antibody detects endogenous levels of total PGRMC2.
Target Information
PGRMC2 (Progesterone Receptor Membrane Component 2), also known as DG6 or PMBP, is a single-pass membrane protein of the cytochrome b5 family (MAPR subfamily). Expressed in sperm, it may function as a steroid receptor and participate in the progesterone-dependent sperm acrosome reaction. PGRMC2 shares about 50% sequence identity with PGRMC1. Loss of PGRMC2 gene is associated with metastasis in uterine endocervical adenocarcinomas, suggesting its role in metastasis suppression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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