Thermo Fisher Scientific HERV-FRD Polyclonal Antibody
Human HERV-FRD 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot에 적합. N-terminal 합성 펩타이드(aa 35-84)를 면역원으로 사용. 고순도 Affinity Chromatography 정제, 액상 형태로 제공. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 0.2–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human HERV-FRD (aa 35–84) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2608413 |
Product Specific Information
- Peptide sequence: TGSPYSTNCW LCTSSSTETP GTAYPASPRE WTSIEAELHI SYRWDPNLKG
- Sequence homology: Human: 100%
Target Information
Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost, or modified their original function during evolution. This endogenous envelope protein has retained its original fusogenic properties. HERV-FRD can make pseudotypes with MLV, HIV-1, or SIV-1 virions and confer infectivity.
Human endogenous retroviruses (HERVs) make up approximately 8% of the human genome. Although most HERVs are nonfunctional, the HERV-W (ERVWE1; MIM 604659) and HERV-FRD envelope (env) proteins can induce cell-cell fusion when expressed in cells possessing appropriate receptors (Blaise et al., 2003 [PubMed 14557543]). [supplied by OMIM]
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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