Thermo Fisher Scientific CTU2 Polyclonal Antibody
Human CTU2 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 및 ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol 버퍼에 보존됩니다. 연구용으로만 사용 가능하며, CTU2 관련 tRNA 2-thiolation 연구에 활용됩니다.
- 카탈로그번호
- PA559441
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CTU2. Recombinant protein control fragment (Product #RP-98583) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2640244 |
Product Specific Information
Immunogen sequence:
LSPDSFCLGF SEGAACGQSL EERSKTLAEV KPILQATGFP WHVVALEEVF SLPPSVLWCS AQELVGSEGA YKAAVDSFLQ QQH
Antigen sequence identity:
- Mouse: 69%
- Rat: 70%
Target Information
Cytoplasmic tRNA 2-thiolation protein 2 (CTU2), also known as C16orf84 or NCS2, is a 515 amino acid protein belonging to the CTU2 family.
C16orf84 localizes in the cytoplasm and plays a central role in 2-thiolation of mcm5S2U at tRNA wobble positions of tRNA(Lys), tRNA(Glu), and tRNA(Gln).
It may act by forming a heterodimer with CTU1/ATPBD3 that ligates sulfur from thio-carboxylated URM1 onto the uridine of tRNAs at wobble position.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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