Thermo Fisher Scientific NAB2 Polyclonal Antibody
Thermo Fisher Scientific의 NAB2 Polyclonal Antibody는 인간 NAB2 단백질을 인식하는 토끼 IgG 폴리클로날 항체로, Western blot 및 Immunoprecipitation에 적합합니다. 고순도 항원 친화 크로마토그래피로 정제되어 있으며, 4°C 단기 및 -20°C 장기 보관이 가능합니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific NAB2 Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Immunoprecipitation (IP)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 196–420 of Human NAB2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris Glycine, pH 7, with 20% glycerol |
| Contains | 0.01% Thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2547570 |
Product Specific Information
- Recommended positive controls: 293T, A431, Jurkat, Raji
- Predicted reactivity: Mouse (93%), Rat (96%), Rhesus Monkey (100%), Bovine (99%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Transcriptional control is regulated by interactions between DNA-bound transcription factors, such as Egr-1/NGFI-A, and coregulatory proteins, such as NAB (NGFI-A-binding proteins). NAB1 and NAB2 are evolutionarily conserved corepressors of EGF-1/NGFI-A.
Both NAB1 and NAB2 contain:
- N-terminal NAB conserved domain 1 (NCD1) for NGFI-A binding
- C-terminal NCD2 domain responsible for repressor function
NAB2 is mainly localized in the nucleus and may play a role in downregulating NGFI-A activity and controlling cell division, differentiation, and apoptosis.
It has a predicted molecular mass of 56 kDa and localizes to chromosome 12q13.3–14.1, a region rearranged in several solid tumors, lipomas, and liposarcomas.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 없음)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.